| DNA | RNA |
| 1. DNA is a genetic material. | 1. It is not a genetic material exception-virus. |
| 2. De-oxyribose sugar is present. | 2. Ribose sugar present. |
| 3. Pyrimidine base thymine is present. | 3. Uracial in place of thymine. |
| 4. It is double helical structure. | 4. It is single helical structure. |
