Differences of DNA and RNA are following:–
| DNA | RNA |
| 1. It usually occurs inside nucleus and some cell organelles. | Very little RNA occur inside nucleus. Most of it is found in the cytoplasm. |
| 2. It is a genetic material. | It is not the genetic material except in certain viruses. |
| 3. It has deoxyribose sugar. | It has ribose sugar. |
| 4. It is usually double stranded. | It is single stranded except in certain viruses e.g. Reoviruses. |
| 5. It has thymine as one of the nitrogenous bases. | Thymine is replaced by uracil in RNA. |
| 6. It replicates to form new DNA molecule. | It normally cannot replicate itself. |
| 7. DNA transcribes genetic information to RNA. | It translates the transcribed message to form polypeptide. |
