Correct option: (D) Both (A) and (B)
Explanation:
Hexokinase and glucokinase are involved in the phosphorylation of glucose to glucose 6- phosphate. The enzyme hexokinase, present in almost all the tissues, catalyses the phosphorylation of other hexose also (fructose, mannose). It has low Km for substrates (about 0.1 mM) and is inhibited by glucose 6- phosphate. In contrast, glucokinase is present in liver, catalyses the phosphorylation of only glucose, has high Km for glucose (10 mM) and is not inhibited by glucose 6-phosphate
