Question

Aldosterone

A. Is a steroid hormone secreted by the adrenal medulla.

B. Production ceases following removal of the kidneys and their juxtaglomerular cells.

C. Production decreases in treatment with drugs which block angiotensin-converting enzyme.

D. Secretion results in increased potassium reabsorption by the nephron.

E. Secretion results in a fall in *** pH.

Answer 1

A. False It is a steroid as its name suggests but is secreted by the adrenal cortex.

B. False Some aldosterone is secreted in response to ACTH secretion, high K+ intake, heart ***, etc. in addition to activity in the renin/angiotensin system.

C. True ACE inhibitor drugs tend to reduce the level of angiotensin II which stimulates the adrenal cortex to produce aldosterone.

D. False It increases potassium secretion in exchange for sodium.

E. True It increases H+ secretion also in exchange for sodium.