| S.No. | Prokaryotic | Eukaryotic |
| 1. | Unicellular organisms. | Unicellular or multicellular organisms. |
| 2. | Lack membrane bound nucleus. | Definite mucleus is present bound by nuclear membrane. |
| 3. | Organelles like mitochondria, endoplasmic reticulum are absent. | Organelles like mitochondria, endoplasmic reticulum are present. |
| 4. | Eg : Amoeba. | Eg : Oedogonium. |
