| Skeletal Muscle | Cardiac Muscle |
| (i) Known as striped muscle | (i) Known as heart muscle. |
| (ii) Voluntary in function | (ii) Involuntary in function |
| (iii) Several nuclei, peripherally placed | (iii) One or more nuclei centrally placed. |
| (iv) Attached to the skeleton in trunk, limbs, and head | (iv) Found only in the walls of heart chambers |
| (v) Intercalated disc absent. | (v) Intercalated disc present. |
| (vi) Powerful and rapid contraction seen | (vi) Rhythmical contraction and relaxation seen |
