(1) Central dogma of molecular biology was postulated by EH.C. Crick in 1958.
(2) DNA gets transcribe to form m-RNA, mRNA acts as a messenger and gets translated to form a polypeptide chain (protein) having specific amino acid sequence.
(3) This unidirectional flow of information from DNA to RNA and from RNA to proteins is referred as central dogma of molecular biology.
(4) Temin (1970) and Baltimore (1970) : Central dogma in retroviruses.
